Banca de QUALIFICAÇÃO: JONAI PACHECO DIAS

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : JONAI PACHECO DIAS
DATE: 25/05/2021
TIME: 14:00
LOCAL: Sala virtual
TITLE:

EPIDEMIOLOGICAL AND MOLECULAR STUDY OF CHIKUNGUNYA VIRUS IN RIO GRANDE DO NORTE IN 2019 AND 2020.

KEY WORDS:

arbovirolgy; chikungunya virus; epidemiology

 

PAGES: 107
BIG AREA: Ciências Biológicas
AREA: Microbiologia
SUMMARY:

Once considered a third world disease, chikungunya fever is currently one of the main emerging arboviruses globally. Shortly after having been established as an autochthonous disease in Brazil, CHIKV spread in the State of Rio Grande do Norte, where it has caused recurrent outbreaks. Because it is a multicausal disease, several factors may be favouring the constant viral circulation within the state. The chronic and disabling aspect of the infection represents one of the main concerns in the field of public health. In this study, samples from several municipalities in Rio Grande do Norte, including the capital city of Natal, were assessed. The epicentre of the cases in the state was also checked, as well as factors that may contribute to the phenomenon of virus spread. A total of 540 samples were tested using qRT-PCR technique, of which 134 were chikungunya positive in the years 2019 (n = 82) and 2020 (n = 52), representing a total of 25% in both years. The largest affected population was the female group (60%) in the age group between 20 and 39 years old. The most frequent complaints presented were fever (65%), headache (48%) and arthralgia (47%). The highest viral load was found on day 0 of the infection. Among the percentages obtained, two probable cases of congenital chikungunya were found, among the newborn group (1.5%) and two asymptomatic cases (1.5%). The highest proportion of cases in 2019 was observed in Natal, in the Tirol neighborhood (57%); and in 2020, in the municipality of Guamaré (33%). The trend of the epicenter of these cases was found in a region close to the Metropolitan Region of Natal. This study contributes to the CHIKF population-based surveillance in Rio Grande do Norte, outlining higher incidence areas, which is useful as a basis for the CHIKV epidemiological control.

BANKING MEMBERS:
Externa ao Programa - 1149507 - FABIANA LIMA BEZERRA
Interno - 348473 - JOSE VERISSIMO FERNANDES
Presidente - 1715230 - JOSELIO MARIA GALVAO DE ARAUJO