Síntese e caracterização de nanocápsulas de finasterida em biopolímero para aplicação cosmética
Nanocapsules, Silk fiber, Finasteride, Nanoencapsulation, Controlled release
Trends and advances in the use of nanoparticles (NPs) in cosmetics, covering 30 years (1993–2023). Based on 2,270 documents extracted from Scopus®, the research revealed an average annual growth of 18.26% in publications, led by countries such as China and India, with significant funding from institutions such as the National Natural Science Foundation of China (NSFC). Organic, inorganic and carbon NPs stood out for contributing to more effective, safe and sustainable cosmetic formulations. A notable advance was the synthesis and characterization of finasteride nanocapsules in biopolymers, such as chitosan, which demonstrated high encapsulation efficiency, stability and biocompatibility, with sizes of 50-200 nm, ideal for hair applications such as alopecia treatment. These nanocapsules, analyzed by electron microscopy and spectroscopy, offer controlled release and low toxicity, enhancing innovations in nanocosmetics. Despite progress, challenges related to toxicity and regulation persist, requiring greater attention. This study consolidates the relevance of nanocosmetics, highlighting the integration of advanced technologies and pointing out future directions for the development of innovative and sustainable solutions in the sector, with the potential to transform the cosmetics industry through safer and more effective formulations.