Banca de DEFESA: DANIELLA NATHALIA ROCHA DO NASCIMENTO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : DANIELLA NATHALIA ROCHA DO NASCIMENTO
DATE: 16/04/2025
TIME: 14:30
LOCAL: On-line - https://meet.google.com/usy-pper-jgj
TITLE:

DEVELOPMENT OF CROSS-LINKED NANOFIBROUS MEMBRANES FOR CONTROLLED RELEASE OF ESSENTIAL OILS WITH ANTIMICROBIAL ACTIVITY

KEY WORDS:

Advanced textiles; Antimicrobials; Membranes; Nanofibers; Blowspinning; Cross-linking.

PAGES: 92
BIG AREA: Engenharias
AREA: Engenharia Química
SUBÁREA: Tecnologia Química
SPECIALTY: Têxteis
SUMMARY:

The development of multifunctional textile materials with a nanometric structure and potential for high-tech applications, using natural components with reduced environmental impact, is the focus of this research. In this context, this study aims to produce water-resistant, sustainable, and biocompatible nanofibrous membranes for the controlled release of antimicrobial natural essential oil derived from cloves (Syzygium aromaticum). Polyethylene oxide (PEO, 200,000 g/mol) polymeric membranes were produced using the electrospinning method, followed by thermal curing with the crosslinking agent tetraethyl orthosilicate (TEOS) to optimize the chemical and mechanical resistances of the PEO fibers. After optimizing the electrospinning and curing methodologies, new membranes were produced with clove essential oil (2 and 5% m/m). The samples were characterized using analytical techniques such as scanning electron microscopy (SEM-FEG), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and thermogravimetric analysis (TG/DTG). The micrographs confirmed that the membranes were composed of fibers with diameters starting at 87 nm. The highest spinning efficiency was achieved with PEO solutions at 10% (m/m) in a 50:50 (m/m) acetone:chloroform mixture, at 90 °C and an injection flow rate of 0.5 mL/min, resulting in membranes with higher yield, fiber density, and handling resistance. The crosslinking of PEO was confirmed by solubility and contact angle tests with water, showing increased hydrophobicity and insolubility of the material. SEM-FEG, XRD, TG/DTG, and FTIR analyses indicated chemical and structural changes that improved the thermal and chemical resistances of the crosslinked PEO. Antimicrobial activity analyses revealed the formation of an inhibition zone around the crosslinked PEO nanofibrous membranes containing 5% (m/m) clove essential oil against E. coli, which remained for 7 days, indicating continued activity of the new material due to the controlled release of the natural active encapsulated by the polymeric fibers. FTIR spectra revealed the presence of eugenol in the membranes, validating the presence of the oil and its main active compound. The produced membranes demonstrated potential for various technological applications, such as dressings, filters, disinfectant films, cosmetics, and active packaging, highlighting the relevance of the obtained results for innovation in the field of advanced textile materials

COMMITTEE MEMBERS:
Externo à Instituição - ANDREA ZILLE
Interna - ***.694.424-** - HELOISE OLIVEIRA MEDEIROS DE ARAÚJO MOURA - UFRN
Presidente - 2614285 - KESIA KARINA DE OLIVEIRA SOUTO SILVA
Externa ao Programa - 1805556 - LUCIENE DA SILVA SANTOS - UFRNInterna - 2614274 - MICHELLE CEQUEIRA FEITOR