Banca de DEFESA: MARCELO SOUZA ARAUJO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : MARCELO SOUZA ARAUJO
DATE: 09/12/2025
TIME: 08:30
LOCAL: Sala 18 ML/FACISA
TITLE:

EFFECTS OF A CONVENTIONAL INTRADIALYTIC REHABILITATION PROGRAM VERSUS ADAPTED WITH INSPIRATORY MUSCLE TRAINING FOR INDIVIDUALS WITH CHRONIC KIDNEY DISEASE: PROTOCOL FOR A RANDOMIZED CLINICAL TRIAL

KEY WORDS:

Renal Insufficiency, Chronic; Renal Dialysis; Exercise Therapy; Physical Therapy.

PAGES: 52
BIG AREA: Ciências da Saúde
AREA: Fisioterapia e Terapia Ocupacional
SUMMARY:

INTRODUCTION: Chronic Kidney Disease (CKD) is characterized by the inability of the kidneys to adequately filter blood and maintain systemic homeostasis. Individuals diagnosed with this condition frequently present multiple adverse effects across different organ systems, notably reduced muscle strength, a condition often associated with protein degradation and consequent generalized muscle atrophy. Physical exercise is essential in the management of this population and may promote improvements in quality of life. Inspiratory Muscle Training (IMT), which has demonstrated efficacy in increasing respiratory muscle strength, has emerged as a relevant strategy to complement rehabilitation in these individuals. OBJECTIVE: To compare a conventional intradialytic cardiovascular and metabolic rehabilitation protocol with a conventional protocol combined with inspiratory muscle training in patients with CKD undergoing hemodialysis. METHODS: A randomized, controlled clinical trial, blinded to the evaluator and statistician. The target population included individuals diagnosed with CKD undergoing hemodialysis at the Santa Rita Nephrology Center in Santa Cruz, RN, Brazil. The following outcomes were assessed: social, anthropometric and clinical profile; Exercise Tolerance, Maximal Respiratory Pressures, Pulmonary Function, Peripheral Muscle Strength, and Quality of Life. Participants were randomized into a Control Group (conventional training: aerobic + resistance training) and an Intervention Group (conventional training + IMT). The intervention lasted 12 weeks, and all participants were reassessed at the end of the final week. Statistical analyses were performed using GraphPad Prism. Two-Way ANOVA was applied for intra- and intergroup comparisons, and a p-value <0.05 was considered statistically significant. RESULTS: Twenty-one individuals participated in the study, with 10 in the Intervention Group (IG), with a mean age of 52 years and a 70% male prevalence. The Control Group (CG) consisted of 11 people, with a mean age of 54 years, predominantly female (54.5%). Exercise tolerance improved in both the IG and CG, although without significance when comparing the groups. MIP increased only in the IG, but there was a change when comparing the groups, as did lower limb strength. Regarding pulmonary function, there was an improvement in forced vital capacity and peak expiratory flow both in the CG individually and when comparing the groups. The other variables, including health-related quality of life, did not show significant effects. CONCLUSION:Some changes were observed in the outcomes of exercise tolerance, MIP (maximum inspiratory pressure), lower limb strength, forced vital capacity, and peak expiratory flow.

COMMITTEE MEMBERS:
Presidente - 2211046 - LUCIEN PERONI GUALDI
Externa ao Programa - 5566309 - VANESSA REGIANE RESQUETI FREGONEZI - UFRNExterna à Instituição - JESSICA DANIELLE MEDEIROS DA FONSECA - EBSERH