Banca de QUALIFICAÇÃO: SEBASTIAO PACHECO DUQUE NETO

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
DISCENTE : SEBASTIAO PACHECO DUQUE NETO
DATA : 18/12/2017
HORA: 14:00
LOCAL: Auditório do Museu de Ciências Morfológicas
TÍTULO:

Subparaventricular zone (SPVZ) in the common Marmoset, Callithrix jacchus: to extended circadian rhythm system 

PALAVRAS-CHAVES:

Hypothalamus. Subparaventricular zone. Calbindin. Callithrix jacchus.

PÁGINAS: 55
GRANDE ÁREA: Ciências Humanas
ÁREA: Psicologia
RESUMO:

The circadian timing system is composed of a set of neural structures responsible for the generation and modulation of the circadian rhythms of mammalian organisms. The suprachiasmatic nucleus (SCN) of the hypothalamus is the structure that generates the circadian rhythmicity, with the 24h environmental light-dark cycle (LD) being its main synchronizer. The SCN generates the expression of circadian rhythms in various diencephalic, telencephalic, and forebrain neural structures. Recently, the concept of "extended circadian rhythm system" has been proposed, considering that there are more than 100 neural structures that could compose the circadian timing system. Of the different regions involved in this context, the subparaventricular zone (SPVZ), the main reference of the SCN, has been highlighted, although it has not yet been studied, especially in non-human primate species such as the common marmoset (Callithrix jacchus). The objective of our study is to describe, through immunohistochemical techniques, the cytoarchitecture, neurochemical component and retinal projection of the SPVZ of marmoset. From the preliminary results, it was not possible to describe SPVZ cytoarchitecture through the Nissl method. Our data demonstrate the SPVZ located between the dorsal portions of the SCN and anterior portions of the paraventricular hypothalamic nucleus (PVH), distributing laterally to the third ventricle, not occupying periventricular portions. The neurochemical content of calcium-binding proteins showed immunoreactive neurons for calbindin (CB), but not for parvalbumin (PV) and calretinin (CR). CB + neurons present a posteromedial path towards the dorsomedial hypothalamic nucleus (DMH), the main efferent of SPVZ. It was also possible to observe a bilateral distribution of axonal terminals of the retinohypothalamic tract (RHT) immunoreactive to the b subunit of the cholera toxin (CTb), which shows direct projection of the retina to this region. A next step of our study will be the morphological description of the immunoreactive neurons for CB and axonal terminals of RTH.

MEMBROS DA BANCA:
Presidente - 2351800 - JEFERSON DE SOUZA CAVALCANTE
Externo à Instituição - JOSÉ RODOLFO LOPES DE PAIVA CAVALCANTI - UERN
Interno - 2140860 - ROVENA CLARA GALVAO JANUARIO ENGELBERTH