Detection of HPV mRNA in self-sampling as marker for cervical cancer screening
Self collection - mRNA - HPV - Uterine cervical cancer
Persistent infection with the Human Papillomavirus (HPV) can be a precursor to cervical cancer, which in turn is considered one of the main causes of cancer deaths in women worldwide. Self-collection is a form of screening that allows women to collect their own samples for HPV detection, and has been considered a promising alternative to screening for uterine cervical cancer screening. In the present study, we investigated the effectiveness of the self- collected mRNA test to detect HPV with carcinogenic potential. To this end, searches were carried out in the following databases: PubMed, Embase, Scopus, Web of Science and LILACS, in which no language or publication period restrictions were applied. Cross-sectional observational studies were included and reviews and meta-analyses, as well as protocols or conferences, were excluded.