QUICK REVIEW OF 100% AFTER ROUTINE SCREENING IS EFFECTIVE IN SCREENING OF FALSE NEGATIVE RESULTS APPLIED AS INTERNAL QUALITY CONTROL IN CERVICAL CYTOPATHOLOGY
Internal quality control, false negative, cervical cytology
The cervical cancer prevention programs are based on screening tests that prove their efficiency in many countries where such programs are organized. However, these tests must have good diagnostic acurária. The cytopathology used worldwide is able to identify treatable injuries and has significant involvement with the decrease in mortality due to this disease. The rates of false negative results of cervical screening is one of the crucial points that have led to the development of several corrective strategies for the implementation of quality control. Studies have shown that an efficient method to detect false negative results is the quick review of 100% in smears considered negative in the first screening. In order to analyze the effectiveness of this methodology as efficient method to be applied as internal quality control, It was peformed a cut cross-sectional study conducted in the laboratory of Cytology Pharmacy College UFRN. 8677 were Quick Review of 100% after routine screening is useful in testing of false negative results applied as internal quality control in cervical cytopathology
The cervical cancer prevention programs are based on screening tests that prove their efficiency in many countries where such programs are organized. However, these tests must have good diagnostic acurária. The cytopathology used worldwide can identify treatable injuries and has significant involvement with the decrease in mortality due to this disease. The rates of false negative results of cervical screening are one of the crucial points that have led to the development of several corrective strategies for the implementation of quality control. Studies have shown that an efficient method to detect false negative results is the quick review of 100% in smears considered negative in the first screening. To analyze the effectiveness of this methodology as an efficient method to be applied as an internal quality control, It was performed a cut cross-sectional study conducted in the Laboratory of Cytology Pharmacy College UFRN. 8677 were analyzed cervical smear material present in the first ballot 8155 (93.98%) Negative smears, 348 (4.02%) as unsatisfactory and 174 (2.0%) as changed. The 8155 smears considered negative after rapid review of 100% were classified 7348 (90.10%) as negative, 552 (6.77%) as unsatisfactory and 255 (3.13%) as abnormal Of the 255 diagnoses were categorized as amended 160 (62.75%) ASC-US, 4 (1.57%) cases of ASC-H, 69 (27.05%) of LSIL, HSIL cases 15 (5.88 %) and 07 (2.75%) cases of AGC, which when compared to the final diagnosis classified as gold standard, presented the following results for sensitivity calculation for ASC-US 94.50% (CI: 89.5 to 97.8), ASC-H 0.0% (CI: 0.0 to 84.2) LSIL (100% 94.3 to 100%), HSIL100% (63.6 to 98.5) AGC 100 (47.8 -100). For specificity were found the following ASC-US percentage 99.5% (CI: 99.3 to 99.6, ASC-H 100% (CI: 99.9 to 99.9), LSIL99,9% (CI: 99 , 8 to 99.9), HSIL 100% (CI: 99.9 to 100), AGC 100% (CI: 99.9 to 99.9). To calculate the positive predictive value were found the following ASC-US 75.6% percentage, ASC-H 0.0, 91.3 LSIL, HSIL 100%, AGC 71.4%. For negative predictive value calculation were found the following ASC-US 99.9% percentage, ASC-H 100%, 100% LSIL, HSIL 100%, AGC 100%. We concluded that the rapid review of 100% of smears considered negative in the first screening appears to be an efficient method as an internal control method quality.