Banca de QUALIFICAÇÃO: MARIA EDUARDA DA FONSECA MENDES SILVA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : MARIA EDUARDA DA FONSECA MENDES SILVA
DATE: 12/08/2024
TIME: 17:00
LOCAL: REMOTA - https://meet.google.com/xsq-rwmw-row
TITLE:

Transcranial direct current stimulation improves pain in end-stage renal disease: a randomized controlled trial.

KEY WORDS:

Chronic pain; rehabilitation; neuromodulation; noninvasive brain stimulation; hemodialysis

PAGES: 15
BIG AREA: Ciências da Saúde
AREA: Fisioterapia e Terapia Ocupacional
SUMMARY:

Background: Patients affected by chronic kidney disease present a high prevalence worldwide. One of the main symptoms associated with kidney dysfunction is chronic pain. In this sense, strategies focusing on the central nervous system are important to control pain symptomatology. Transcranial direct current stimulation (tDCS) is a non-invasive and easy-to-use method that could be used to improve pain in a several chronic condition. Objective: Evaluate the effects of anodal M1-SO tDCS on pain, fatigue, and functional performance, in patients affected by end-stage renal disease. Method: This double-blind, two-arm, parallel, randomized, sham-controlled study was conducted between October 2023 and April 2024 at the Kidney Institute in Natal, Brazil. Thirty-four patients with end-stage renal disease undergoing hemodialysis and experiencing chronic pain (visual analogue scale > 4) were randomized for active or sham group (n=17). Anodal tDCS over C3 with an intensity of 2mA was administered in 15 sessions, 3 times per week. Visual analogue scale for pain (VAS) (primary outcome), fatigue, functional performance (sit-to-stand test, stationary walk, timed up and go test, elbow flexion test, and manual dynamometry) was assessed, and a GEE was used for statistical analysis. Results: It was found a significant difference in VAS (p < 0.001) and timed up and go (p = 0.009) between groups. No significant differences between groups were observed for fatigue (p = 0.21) and all others functional performance test. Conclusion: This study demonstrates that tDCS may be considered a good strategy to improve pain and functional mobility in patients affected by end-stage renal disease patients undergoing hemodialysis. 

COMMITTEE MEMBERS:
Externa ao Programa - 1081828 - CATARINA DE OLIVEIRA SOUSA - nullExterna ao Programa - 1143199 - MARIA DO SOCORRO LUNA CRUZ - nullPresidente - 2646619 - RODRIGO PEGADO DE ABREU FREITAS