Banca de DEFESA: THAIS SOUSA RODRIGUES GUEDES

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : THAIS SOUSA RODRIGUES GUEDES
DATE: 12/04/2023
TIME: 09:00
LOCAL: REMOTA - https://meet.google.com/cav-soux-aib
TITLE:

SEXUAL DYSFUNCTION IN WOMEN WITH CANCER: SYSTEMATIC REVIEW AND RETROSPECTIVE COHORT STUDY

KEY WORDS:

Oncology, Sexual dysfunction, Longitudinal study, Systematic review.

PAGES: 103
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

The process of becoming ill with breast cancer, associated with changes resulting from treatments, result in major changes in sexuality. This study aimed to: A) Systematically review the scientific literature on the risk of developing sexual dysfunction in adult women who have undergone treatment for cancer. B) To analyze the risk of sexual dysfunction in women who survived breast cancer compared to the group of women without a history of cancer. Two studies were carried out - A) Systematic review of the literature according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The following databases were consulted: Pubmed, Lilacs, Scielo, Cinahl, Scopus and Web of Science. The descriptors were: Cancer, neoplasms, “Sexual Dysfunction”, “sexual function” and women. To assess the quality of evidence, the Assessing the Quality of Observational Cohort and Cross-Sectional Studies tool was used. B) Retrospective cohort study, the sample consisted of women diagnosed with breast cancer for at least one year and who underwent treatment (exposed group), and by women from the community who do not have a history of breast cancer (group not exposed). Data collection was performed using the medical records of patients diagnosed with breast cancer and individual interviews using the validated Female Sexual Function Index (FSFI) questionnaire for patients with and without breast cancer. Sixteen articles were included in the study A, through which it was possible to identify that sexual dysfunction in cancer patients was present in all studies, except 2, its incidence varied between 30% and 80%, and the risk for the development of sexual dysfunction increases between 2.7 and 3.5 times in women who have had breast and cervical cancer. Participated in the second study (B), 90 women from the exposed group and 93 women from the non-exposed group. Women in the cancer-exposed group are 3.9 times more likely to have sexual dysfunction when compared to non-exposed women (OR: 3.9; CI: 1.8-8.2; p <0.001), with the incidence of dysfunction sexual dysfunction equal to 74% in this group, the presence of comorbidities increases the chances by 2.5 times for the occurrence of sexual dysfunction (OR: 2.5; CI: 1.2-4.9; p =0.009). It is concluded that women with cancer have a 2.7 to 3.5 times greater risk of presenting sexual dysfunction, and specifically in women with breast cancer investigated retrospectively, the chances for this public were 3.9 times greater compared to women without a history of cancer, thus, breast cancer is a risk factor for sexual dysfunction in women with this neoplasm.

COMMITTEE MEMBERS:
Externa à Instituição - MARIANA MAIA DE OLIVEIRA SUNEMI - UFMG
Presidente - 3926907 - DYEGO LEANDRO BEZERRA DE SOUZA
Externa ao Programa - 2305247 - ISABELLE RIBEIRO BARBOSA MIRABAL - nullExterna ao Programa - 2786809 - MARIA THEREZA ALBUQUERQUE BARBOSA CABRAL MICUSSI - nullExterna à Instituição - MARIANNA DE CAMARGO CANCELA - INCA