Banca de QUALIFICAÇÃO: EVELLYN CÂMARA GRILO

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : EVELLYN CÂMARA GRILO
DATE: 10/03/2021
TIME: 08:30
LOCAL: DEFESA REMOTA - https://meet.google.com/fvu-waeb-uid
TITLE:

EFFECT OF ZINC SUPPLEMENTATION ON BONE DENSITY AND MINERAL CONTENT IN PATIENTS WITH DUCHENNE MUSCULAR DYSTROPHY.


KEY WORDS:

Zinc, bone health, muscular dystrophies.


PAGES: 24
BIG AREA: Ciências da Saúde
AREA: Nutrição
SUMMARY:

This study aimed to evaluate the effect of zinc supplementation on the density and bone mineral content in patients with Duchenne muscular dystrophy (DMD). Thirty-four volunteers (5.0 to 24.2 years) with a positive genetic test for DMD were included in this clinical trial. Data acquisition was performed in three stages (T0, T1, and T2) with an interval of four months in between. All participants received oral supplementation with zinc bis-glycine chelate between T1 and T2. The daily dose was adjusted for age: 5mg (4 to 8 years); 10mg (9 to 13 years); 15mg (≥14 years) to avoid exceeding the tolerable upper intake level. Total body and lumbar spine (g/cm2 and z-score) bone mineral density (BMD) and content (BMC) were performed using dual emission x-ray absorptiometry (DXA). Data normality was verified using the Shapiro-Wilk test, and the comparison between the times was performed using a mixed linear model. The bone parameters did not differ significantly (p>0.05) between the different evaluation times. Zinc supplementation did not influence on bone parameters of patients with DMD.


BANKING MEMBERS:
Presidente - 1216686 - JOSE BRANDAO NETO
Interna - 175.476.444-49 - LUCIA DE FATIMA CAMPOS PEDROSA - UFRN
Externa ao Programa - 4659679 - SANCHA HELENA DE LIMA VALE
Externa ao Programa - 1452705 - SEVERINA CARLA VIEIRA CUNHA LIMA
Notícia cadastrada em: 01/03/2021 15:25
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