Banca de QUALIFICAÇÃO: JOAO FERREIRA DE MELO NETO

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
STUDENT : JOAO FERREIRA DE MELO NETO
DATE: 06/12/2020
TIME: 14:00
LOCAL: Sala de Aula do PPGCSa
TITLE:

ANALYSIS OF THE VENOUS DRAINAGE IN PATIENTS WITH DURAL ARTERIOVENOUS FISTULA – CORRELATION WITH THE CLINICAL PRESENTATION

KEY WORDS:

DURAL ARTERIOVENOUS FISTULA, CEREBRAL VENOUS DRAINAGE, BRAIN HEMORRHAGE 

PAGES: 15
BIG AREA: Ciências da Saúde
AREA: Medicina
SUMMARY:

Backgroud and Purpose – Dural arteriovenous fistulas (DAVF) are acquired pathological arteriovenous communications located in the dural layers. The symptoms range from minor, such as pulsatile tinnitus to major like those associated to brain hemorrhage and are related to the venous anatomy of the patient. The objective of the study was to identify which elements in the venous anatomy would be relevant for the development of symptoms.

            Methods – Retrospective analysis of angiographies from 3 centers of patients above 18 years of age, with a single DAVF. The patients were classified in a group with minor symptoms (group 1) and a group with major symptoms (group 2). In group 2 the patients were classified as 2a – hemorrhage and 2b – major symptoms not related to hemorrhage. The angiography was evaluated for the presence of anatomic factors causing restriction to the DAVF and/or brain parenchyma.

Results – The prevalence of stenosis in the DAVF draining veins and the presence of tiny anastomosis was significantly higher in group 2, respectively 32,6% and 19,1% in comparison to group 1, that was respectively 2,68% and 5,36%. The prevalence of stenosis in the DAVF draining veins was significantly higher in group 2a (51,1%) in comparison to group 2b (11,9%). The DAVF drainage through the main venous outlet, the absence of a alternate venous outlet and contrast stagnation in the brain parenchyma were significantly higher in group 2b, respectively 85%, 45% and 62,5% in comparison to group 2a, respectively 53%, 17% and 29,8%.

Conclusions – Major symptoms were observed when the residual drainage capacity of the brain tissue was exhausted because of DAVF competition (predominance in group 2b) or when the DAVF draining veins had anatomical features leading to a impaired drainage, causing venous hypertension in the venous side of the DAVF (predominance in group 2a).

BANKING MEMBERS:
Interno - 346138 - ALDO DA CUNHA MEDEIROS
Presidente - 1048067 - ANTONIO MANUEL GOUVEIA DE OLIVEIRA
Externo ao Programa - 1369275 - CLECIO DE OLIVEIRA GODEIRO JUNIOR