Banca de DEFESA: TATIANE ANDREZA LIMA DA SILVA

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
DISCENTE : TATIANE ANDREZA LIMA DA SILVA
DATA : 20/11/2018
HORA: 09:00
LOCAL: Departamento de Educação Física
TÍTULO:

Influence of curcumin on energy metabolism, body composition and lipid profile of people living with HIV/AIDS


PALAVRAS-CHAVES:

curcumin, dyslipidemia, HIV/AIDS


PÁGINAS: 50
GRANDE ÁREA: Ciências da Saúde
ÁREA: Educação Física
RESUMO:

Objective: To evaluate the influence of curcumin supplementation on the substrate oxidation at rest, body composition and lipid profile of people living with HIV/AIDS (PLHA) under antiretroviral therapy.  Methods: This double-blind, crossover, randomized clinical trial was comprised by 20 subjects arranged in experimental group (EG) and control group (CG), receiving 1,000mg curcumin/day and placebo, respectively, during 30 days. The substrate oxidation at rest was assessed by indirect calorimetry, the body composition was measured by Dual-energy X-ray Absorptiometry, and the lipid profile was evaluated by biochemical tests. Data analysis was performed by independent samples and paired t-tests to compare the difference between groups and times. A p value < 0.05 was accepted as significant.  Results: There was no difference between groups regarding substrate oxidation at rest and body composition. Regarding the lipid profile, an increase in serum triglyceride levels was observed after curcumin supplementation (182 vs. 219mg/dL; p=0.004). Conclusion: Curcumin supplementation (1.000mg/day during 30 days) promoted elevation of serum triglyceride levels in PLHA. Considering the scientific evidence of the potential anti-inflammatory and antioxidant properties of curcumin and its positive effect on the modulation of serum triglycerides, we highlighted the need for additional studies to better understand the impact of curcumin supplementation and its effects on metabolic pathways of lipid metabolism on PLHA. 


MEMBROS DA BANCA:
Presidente - 2626634 - PAULO MOREIRA SILVA DANTAS
Interno - 6349161 - GERALDO BARROSO CAVALCANTI JUNIOR
Externo ao Programa - 4659679 - SANCHA HELENA DE LIMA VALE
Externo à Instituição - ANDERSON MARLIERE NAVARRO - USP
Externo à Instituição - RONALDO VAGNER THOMATIELI DOS SANTOS - UNIFESP
Notícia cadastrada em: 14/11/2018 15:25
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