Banca de DEFESA: ALEXANDRE COELHO SERQUIZ

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
DISCENTE : ALEXANDRE COELHO SERQUIZ
DATA : 27/11/2018
HORA: 08:30
LOCAL: BIOQUÍMICA
TÍTULO:

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(OBTAINING AQUEOUS EXTRACTS FROM PULP, SHELL AND SEED OF ATEMOIA FRUIT (ANNONA CHERIMOLA X ANNONA SQUAMOSA L.): IDENTIFICATION OF ACTIVE COMPONENTS AND EVALUATION OF SOME OF THEIR IN VITRO AND IN VIVO PROPERTIES)

PALAVRAS-CHAVES:

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(Annona x atemoya; Antioxidant proteins; Oxidative stress)

PÁGINAS: 69
GRANDE ÁREA: Ciências Biológicas
ÁREA: Bioquímica
RESUMO:

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(Exposure to the environment, elevated xenobiotic levels in the diet and even the biochemical reactions performed by human metabolism, increase the generation of reactive oxygen species (ROS) and nitrogen (RN) .This increase in ROS and RNA creates an oxidative stress, and it can generate a series of pathophysiological problems. Biochemical studies report that dietary antioxidants have benefits in the prevention of diseases, fruits are distinguished by the large amount of bioactive substances with this beneficial activity. it is not possible to know its chemical components (nutrients) and their effects on the metabolism after its ingestion.Therefore, it is very important to understand the mechanisms of the reaction of the antioxidants present in the atemoia fruit with the reactive species. , of which the formation of aqueous extract and flour of the parts of the sem proteins, carbohydrates and phenolic compounds, as well as the evaluation of the presence of inhibitors of proteases and hemagglutinins, in addition to the antioxidant tests; total antioxidant capacity (CAT), hydroxyl radical sequestration (SRH), superoxide radical scavenging (SRS), metal chelation (QM), and oxidative stress evaluation by biochemical and histological parameters in animals fed the atemoia parts. The presence of protease inhibitors and agglutinins in atemoia extracts have been detected. These substances have the potential to be used in the biotechnology or biomedical area, helping to prevent diseases or even to improve the genetic quality of fruits. The extracts present proteins, carbohydrates and phenolic compounds in their composition, a fact that suggests a synergy between these compounds in the antioxidant effect, it is worth mentioning that the study supposes the presence of other substances not known, which may be influencing these effects. In vivo studies, however, show a nontoxic effect of the extracts. The best in vivo results were obtained with seed extract. Thus, it is proposed that the extracts of atemoia have functional properties. And future studies should be carried out in order to elucidate specific pathways and compounds that can act on these benefits.)

MEMBROS DA BANCA:
Externo ao Programa - 1549705 - ADRIANA FERREIRA UCHOA
Presidente - 2195251 - HUGO ALEXANDRE DE OLIVEIRA ROCHA
Externo à Instituição - MARIA APARECIDA MEDEIROS MACIEL - UnP
Externo ao Programa - 1871916 - RAQUEL BRANDT GIORDANI
Externo à Instituição - THALES ALLYRIO ARAUJO DE MEDEIROS FERNANDES - UERN