Banca de DEFESA: DANYLLO DO NASCIMENTO SILVA JUNIOR

Uma banca de DEFESA de DOUTORADO foi cadastrada pelo programa.
STUDENT : DANYLLO DO NASCIMENTO SILVA JUNIOR
DATE: 13/08/2024
TIME: 09:00
LOCAL: AUDITÓRIO DO DEPARTAMENTO DE ODONTOLOGIA e Google Meet
TITLE:

FACTORS ASSOCIATED WITH MORTALITY OF ELDERLY PEOPLE DUE TO COVID-19

KEY WORDS:

Mortality. SARS-CoV-2. COVID-19. Elderly. Risk factors.

PAGES: 109
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUBÁREA: Epidemiologia
SUMMARY:

The COVID-19 pandemic, triggered by the SARS-CoV-2 coronavirus, represents an unprecedented global public health crisis, with particularly severe impacts on the elderly population. Since its emergence in Wuhan, China, at the end of 2019, the disease has radically reshaped daily life and the functioning of society on a global scale, resulting in an alarming number of deaths and significant economic and social disruption. COVID-19 can manifest asymptomatically or symptomatically, with severity ranging from no symptoms to severe respiratory complications, especially among older people. Older age has been identified as a significant risk factor for severe manifestations and complications of the disease, partly due to the physiological aspects of aging, which affect the effectiveness of the immune system. Thus, the elderly population has become particularly susceptible to the devastating effects of COVID-19. Objective:To analyze the biological and non-biological factors associated with COVID-19 mortality rates in the elderly. Methodology: Various theoretical-methodological approaches were applied, organized by articles as follows: (a) Factors associated with COVID-19 mortality among the elderly: systematic review and meta-analysis protocol; (b) Factors associated with COVID-19 mortality among the elderly: a systematic review with worldwide data; (c) Spatial analysis of socioeconomic and demographic factors associated with COVID-19 mortality among the elderly in Brazil. Results: The findings of this thesis highlight the significant influence of biological and clinical factors on the mortality of older people affected by COVID-19 worldwide. Advanced age emerges as a crucial factor, with mortality rates increasing progressively with advancing age. The presence of comorbidities, such as diabetes, cardiovascular disease, and hypertension, plays a major role in the fatal outcome of the disease. Impaired functional status is also an important predictor of mortality, underscoring the importance of geriatric assessment in identifying prognostic factors. Clinical manifestations and laboratory changes, such as dyspnea, fever, cough, and increased inflammatory markers, are also strongly associated with the severity of the disease and increased mortality in the elderly. These findings underscore the need for a multidisciplinary and personalized clinical approach to the effective management of COVID-19 in elderly patients, considering not only clinical conditions but also functional status and individual risk factors. Conclusion: This study highlighted that advanced age is a critical factor for COVID-19 mortality in older people, influenced by socioeconomic and health conditions. Additionally, women showed higher survival due to biological and behavioral differences. Racial/ethnic minorities and individuals of lower socioeconomic status faced greater risks, reflecting structural inequalities. The study emphasizes the need for integrated public policies to mitigate these disparities and promote equity in future health crises.

COMMITTEE MEMBERS:
Presidente - 2495705 - GRASIELA PIUVEZAM
Interna - 2665457 - GIDYENNE CHRISTINE BANDEIRA SILVA DE MEDEIROS
Externa à Instituição - EVA VEGUE PARRA - UCAM
Externa à Instituição - ELOINA VALERO MERLOS - UCAM
Externa à Instituição - ELLANY GURGEL COSME DO NASCIMENTO - UERN