Banca de QUALIFICAÇÃO: PEDRO VINICIUS MATIAS PIRES

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : PEDRO VINICIUS MATIAS PIRES
DATE: 27/05/2025
TIME: 14:30
LOCAL: VIDEOCONFERÊNCIA
TITLE:

Low-Energy Development of Andiroba and Copaiba Oil Nanoemulsions for Potential Wound Healing Applications

KEY WORDS:

Antimicrobial, nanotechnology, andiroba oil, copaiba oleoresin, nanoemulsion, phase inversion.

PAGES: 91
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUMMARY:

The skin is the largest human organ and has, as one of its main functions, the

protection of other organs located internally in the body. Due to its anatomical position,

this organ is more susceptible to injuries, such as wound formation. The major risk

associated with wounds is potential contamination by microorganisms, which are

combated using antimicrobials—a large class of medications designed primarily to

inactivate bacteria and fungi. However, the improper use of this class of drugs has led

to resistance against many microorganisms, rendering numerous pharmaceuticals

ineffective and highlighting the need for the development of new medications against

these organisms. Andiroba is a tree native to the Amazon region and was already used

for various therapeutic purposes by indigenous peoples before the discovery of the

American continent. Some studies attribute antimicrobial effects to this plant, and to

enhance this effect, the use of nanotechnology was considered, combining its fixed oil

with Copaiba oleoresin. Thus, the objective of this study was to develop and

characterize a nanoemulsion formulation encapsulated with filtered andiroba fixed oil

and Copaiba oleoresin, using the low-shear phase inversion technique. The prepared

formulations were characterized by particle size analysis, Polydispersity Index, Zeta

Potential, Hydrogen Potential, Antioxidant Activity, and Antimicrobial Activity. So far,

stable products have been developed with satisfactory results.

COMMITTEE MEMBERS:
Externa à Instituição - ALESSANDRA DANIELE DA SILVA - UFPE
Interna - ***.782.604-** - ANNE EMMANUELLE CÂMARA DA SILVA MELO - UFRN
Presidente - 3652554 - FRANCISCO CANINDE DE SOUSA JUNIOR