Banca de DEFESA: ÍTALO HENRIQUE MEDEIROS DAMASCENO

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : ÍTALO HENRIQUE MEDEIROS DAMASCENO
DATE: 22/01/2025
TIME: 08:00
LOCAL: Faculdade de Farmácia
TITLE:

Prevalence and risk factors associated with inadequate technique of use of the inhalation device in patients with asthma and COPD

KEY WORDS:

asthma, COPD, inhaler devices, inhalation technique

PAGES: 55
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUBÁREA: Farmácia clínica, assistência e atenção farmacêuticas
SUMMARY:

Asthma and Chronic Obstructive Pulmonary Disease (COPD) are chronic respiratory diseases affecting millions of people worldwide, resulting in high morbidity and mortality. Inadequate use of inhalation devices (IDs) is a critical factor that compromises treatment effectiveness, leading to increased hospitalizations and worsening symptoms. This study aimed to analyze the prevalence of inadequate techniques in the administration of IDs among patients with asthma and COPD, identify critical errors and associated risk factors, and propose pharmaceutical interventions to improve the use of these devices. An observational, cross-sectional study was conducted with 575 patients attended at a pulmonary outpatient clinic in a university hospital and a specialized unit, both in Natal, Brazil. Participants, aged 18 and older with a diagnosis of asthma and/or COPD, completed questionnaires on sociodemographic characteristics and performed inhalation techniques for evaluation. Treatment adherence was assessed using the Morisky-Green-Levine test, while inhalation technique was analyzed using specific checklists for each ID, considering as critical errors those with the highest potential to affect drug effectiveness, such as poor expiration, inadequate sealing around the mouthpiece, improper inspiration, and failure to pause during inhalation. Results showed a high prevalence of inadequate inhalation technique (55.2%), with the most frequent errors being improper inspiration (61.2%) and incorrect inhalation pause (56.6%). Multivariate analysis indicated that factors such as older age (OR: 1.016), lower household income (OR: 2.450), worsening symptoms with exertion (OR: 1.935), and asthma diagnosis (OR: 3.596) are significantly associated with inadequate technique. These findings highlight the complexity involved in using IDs and the need for ongoing educational interventions, especially targeted at vulnerable populations. Implementing training and guidance programs, as well as using checklists during consultations, are suggested strategies to enhance adherence and treatment effectiveness. In conclusion, this study highlights the high prevalence of inadequate techniques in the administration of IDs among patients with asthma and COPD. The identified critical errors and associated risk factors underscore the importance of targeted educational interventions to optimize the use of IDs and, consequently, improve the management of respiratory diseases.

COMMITTEE MEMBERS:
Interna - 347795 - IVONETE BATISTA DE ARAUJO
Presidente - 2432313 - RAND RANDALL MARTINS
Externa à Instituição - YONARA MONIQUE DA COSTA OLIVEIRA - UFCG