Banca de QUALIFICAÇÃO: SARAH DANTAS VIANA MEDEIROS

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : SARAH DANTAS VIANA MEDEIROS
DATE: 02/09/2024
TIME: 13:30
LOCAL: Sala de Aulas II GEP/MEJC
TITLE:

Neonatal Outcomes of Pregnant Women with Pre-Eclampsia

KEY WORDS:

Preeclampsia; neonatal outcomes; maternal outcomes.

PAGES: 33
BIG AREA: Ciências da Saúde
AREA: Farmácia
SUMMARY:

Introduction: Pre-eclampsia (PE) is a multifactorial and multisystemic disease diagnosed by the presence of arterial hypertension after the 20th week of pregnancy, associated with proteinuria and/or target organ dysfunction. It is the main cause of elective prematurity in Brazil and is associated with both maternal and neonatal morbidity and mortality. Commonly related neonatal outcomes include prematurity, low birth weight, respiratory distress syndrome and sepsis. Objective: To evaluate the clinical-laboratory parameters of pregnant women with pre-eclampsia and neonatal outcomes. Method: This is a longitudinal, observational and prospective study, in which 32 pregnant women diagnosed with pre-eclampsia and their respective newborns were followed. To evaluate laboratory parameters (blood count, creatinine, urea, AST, ALT, LDH and ribbon proteinuria), blood and urine samples were collected from pregnant women, as well as maternal and neonatal data from electronic medical records. Results: The median age of pregnant women with early PE was 26 years and that of pregnant women with late PE was 24 years (p=0.175). Pregnant women with early PE had fewer prenatal consultations (p = 0.032), higher diastolic blood pressure values at admission (p = 0.049) and higher urea concentrations (p = 0.029). The median gestational age at birth was 33 weeks and 4 days for pregnant women with early PE and 36 weeks and 1 day for those with late PE (p = 0.004). The median birth weight was 1580g for early PE and 2230g for late PE (p = 0.021). The highest rates of admission to the neonatal intensive care unit (p < 0.001), sepsis (p = 0.014), respiratory distress syndrome (p = 0.003) and need for ventilatory support (p = 0.027) were observed in early pre-eclampsia. Conclusion: Based on the above, early pre-eclampsia has an important impact on neonatal outcomes.

COMMITTEE MEMBERS:
Interna - 1714243 - DANIELLA REGINA ARANTES MARTINS SALHA
Externo à Instituição - KLEYTON SANTOS DE MEDEIROS - LNRCC
Presidente - 1055045 - MARCELA ABBOTT GALVAO URURAHY