Analysis of frequency following response in babies with congenital syphilis
Syphilis, hearing loss, auditory evoked potential, frequency following response, infant.
Study1: To verify which protocols are used for frequency following response (FFR) acquisition in children up to 24 months through a systematic review. And Study 2: To analyze the results of frequency following response in infants with congenital syphilis exposure. Method: In the study: 1 we searched the databases PubMed, LILACS, Web of Science, Scopus, Livivo, psycINFO, as well as gray literature searches and manual searches in the bibliographic references of the included articles. Study 2 was approved by the Research Ethics Committee No. 3,361,064. The partial sample consists of 40 children exposed to syphilis being followed at the pediatric outpatient clinic. An anamnesis and socioeconomic questionnaire were used. All had brainstem auditory evoked potential with click stimulus at 80 dB nNA and V wave presence at 30 dB nNA. They performed the FTA-ABS laboratory test at 18 months and the frequency following response (FFR) with / da / stimulus, lasting 170 ms, velocity of 3.70 / s, at 80dBnNA intensity in both ears. Four promediations of 1000 sweeps were performed, totaling 4000 sweeps, in a window of -40 to 270ms, 100K gain and filter of 30 to 3000 Hz. Partial results: in study 1, 459 articles were identified. After all the selection steps, 14 articles were included that are being tabulated and analyzed. In study 2, to date, 16 patients were recruited, with 11 patients attending the service and 5 patients with completed audiological evaluation. FFR analysis was started.