Banca de QUALIFICAÇÃO: GABRIEL AUGUSTO DUARTE DE PAIVA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : GABRIEL AUGUSTO DUARTE DE PAIVA
DATE: 27/12/2024
TIME: 10:00
LOCAL: https://meet.google.com/ygr-oxcm-aaz
TITLE:

EVALUATION OF MULTIDIMENSIONAL MODELS TO SIMULATE A RELIABLE TEMPERATURE FIELD IN PHOTOTHERMAL THERAPY

 

KEY WORDS:

Heat transfer simulation, Cancer therapy, Melanoma, Realistic tumor

PAGES: 44
BIG AREA: Engenharias
AREA: Engenharia Mecânica
SUBÁREA: Fenômenos de Transporte
SPECIALTY: Transferência de Calor
SUMMARY:

The research focuses on heat transfer as a tool for cancer treatment, which is known as hyperthermia. The theme was chosen based on the increasing importance of this phenomenon for the treatment of cancer. The research simulates a skin cancer tumor, more specifically melanoma, being treated by photothermal therapy (PPT), which is a type of hyperthermia in which the heat source is laser light. For this treatment, it is inevitable to have the laser radiation being absorbed by healthy regions of a tissue, however, there are ways to control the temperature distribution, thus avoiding side effects such as patient discomfort and death of healthy tissues, an example is the use of nanoparticles embedded in the tumor. In this context, computational simulations of heat transfer phenomena can be a powerful weapon to solve the complex governing equations more easily, leading to reliable predictions of the living tissues behavior during the treatment. In this research, two codes, developed in the FORTRAN90 programming language, were applied to find the divergence of the radiation heat flow and the temperature field in the tissue. The main objective of the work is to identify at which points a more complex multidimensional simulation can be advantageous in predicting the results of a real treatment through PTT. The
objective is reached by obtaining reliable 2D and 3D temperature fields, comparing them with a one-dimensional result, simulating a tumor with a more realistic three-dimensional geometry and comparing the results with a cylindrical geometry.

 

COMMITTEE MEMBERS:
Presidente - 2014591 - ANDRE JESUS SOARES MAURENTE
Interno - 3254216 - ALVARO AUGUSTO SOARES LIMA
Externo à Instituição - BERNARD LAMIEN