The aim of this thesis was to develop new catalytic materials through the synthesis of mesoporous silica and carbon supports for Mo impregnation to study its catalytic performance in hydrodeoxygenation of gas-phase platform molecules, where it was tried to determine the influence of the catalyst, support and support/catalyst behavior under different reaction conditions. Mesoporous carbons were obtained using the silica materials as a template. The impregnation of molybdenum oxide (MoO₃) was carried out by the incipient wetness impregnation to obtain an amount of 4 and 2 Mo atoms/nm² in the silica and carbon supports. Characterization was performed using several techniques such as X-Ray Diffraction (XRD), N₂ physisorption, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), by these techniques was possible to confirm the synthesis of the silica and carbon materials and the subsequent impregnation of the molybdenum oxide. The techniques of Programmed Temperature Desorption (TPD) and Oxygen Storage Capacity (OSC) allowed to evaluate the influence of different reaction conditions on MoO₃. The materials were evaluated in hydrodeoxygenation reactions of guaiacol and phenol. The results showed an excellent selectivity in reactions with phenol indicating optimal conditions for the reaction at 400 °C. Among all the catalysts studied, the material supported on the CMK-3 carbon replica presented the best results.