EFFECTIVENESS OF ILIB MODIFIED IN PERIODONTAL CLINICAL PARAMETERS AND GLYCEMIC CONTROL IN PATIENTS WITH PERIODONTITIS AND TYPE II DIABETES – PILOT STUDY
Periodontal disease, Periodontitis, Irradiation Laser Intravenous of Blood, Diabetes Mellitus
Periodontitis and type II diabetes are chronic and worldwide high prevalent conditions with a bidirectional relationship between them. Due to this relationship, the proposition of auxiliary therapies for the treatment of periodontitis in diabetic patients, including the low-intensity laser, is a reality. The low-intensity laser is attached to a bracelet over the radial artery to radiate the blood cells through the technique called modified ILIB (Intravascular Laser Irradiation of Blood), aiming the control of the plasma glucose and chronic inflammatory processes. Therefore, this research evaluated the efficacy of the modified ILIB in improving clinical periodontal parameters, such as HbA1c and fasting blood glucose of patients with periodontitis and type II diabetes on a randomized, double-blinded, longitudinal clinical study. The sample included 21 patients distributed in two groups. The control group (CG) received conventional periodontal treatment (scaling and root planning, and oral hygiene guidance), and the test group (TG) received conventional periodontal treatment and 10 laser applications through the modified ILIB technique. The VPI and GBI hygiene indexes, the clinical periodontal parameters BoP, PD, CAL, the fasting blood glucose levels and HbA1c were evaluated at the baseline (T0) and after 4 months (T4) of treatment for both groups. Partial results showed VPI significant decrease on the TG from 59.98 at T0 to 29.00 at T4 (p < 0.05), while on the CG the decrease was from 58.33 at T0 to 33.00 at T4 (p > 0.05). The GBI decreased an average of 35.30 on the TG and 2.34 on CG without difference at intragroup and intergroup analysis. The BoP median decreased from 50.00 at T0 to 41.50 at T4 (p < 0.05) on the CG, and on the TG reduced from 68.44 at T0 to 42.75 at T4 (p < 0.05). Meanwhile, the PD median decreased from 5.0 mm at T0 to 2.5 mm at T4 (p < 0.05) on the TG, and from 6.0 mm at T0 to 4.0 mm at T4 (p < 0.05) on the CG. For the CAL parameter, there was 1.5 mm clinical attachment improving from T0 to T4 (p < 0.05) on the CG, and an increase of 2.5 mm from T0 to T4 (p < 0.05) on the TG. No differences in HbA1c and fasting blood glucose was observed from T0 to T4 on the intergroup and intragroup analysis.